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  • Title: Solvent-dried and gamma-irradiated tendon allografts in rats. Mechanical and morphological evaluation.
    Author: Maeda A, Horibe S, Matsumoto N, Nakamura N, Mae T, Shino K.
    Journal: J Bone Joint Surg Br; 1998 Jul; 80(4):731-6. PubMed ID: 9699845.
    Abstract:
    We examined solvent-dried, gamma-irradiated (SD-R) allografts and fresh-frozen (FF) allografts mechanically and morphologically. Before transplantation, FF grafts were more than six times stronger than SD-R grafts. After four weeks, the tensile strength was about the same in both groups. At 24 weeks only collagen fibrils of small diameter were observed in the SD-R grafts while in FF grafts fibrils of small and intermediate diameter were seen. Clinically, we suggest that SD-R grafts could be used as a favourable alternative to FF grafts if care was taken regarding their initial mechanical weakness.
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