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  • Title: Two siblings poisoned with diphenhydramine: a case of factitious disorder by proxy.
    Author: Arnold SM, Arnholz D, Garyfallou GT, Heard K.
    Journal: Ann Emerg Med; 1998 Aug; 32(2):256-9. PubMed ID: 9701313.
    Abstract:
    We report a case of factitious disorder by proxy (FDBP), formerly known as Munchausen syndrome by proxy, in which 2 siblings were poisoned with diphenhydramine. Although diphenhydramine is a readily available medication, no report of its use as the sole agent in an FDBP case was found in a literature search. Although sibling involvement in FDBP is well documented, this is the first case report of 2 siblings hospitalized simultaneously because of intentional poisoning with the same substance. Finally, the use of physostigmine to definitively diagnose anticholinergic poisoning in a case of FDBP has not previously been described.
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