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  • Title: Interaction of hyperbaric nitrogen and oxygen effects on behavior.
    Author: Thomas JR, Burch LS, Banvard RA.
    Journal: Aviat Space Environ Med; 1976 Sep; 47(9):965-8. PubMed ID: 971176.
    Abstract:
    Breathing elevated environmental pressures of nitrogen and oxygen produced changes in behavior of rats that evidenced an interaction between the two gases. Rates of responding generated by a fixed-interval schedule of reinforcement systematically changed as partial pressures of nitrogen were elevated from 0.8 to 10.4 ATA. Response rates increased above baseline followed by a decline in rates as a function of increasing nitrogen pressure. Concurrent increases in partial pressures of oxygen from 0.2 to 2.2 ATA potentiated the rate-increasing effects of nitrogen at low to moderate nitrogen pressures and enhanced rate-decreasing effects at higher nitrogen pressures. Raised oxygen pressures modulated and interacted with the narcotic effects of nitrogen on behavior.
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