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  • Title: A comparison of prosthetic materials used to repair abdominal wall defects.
    Author: Mori N, Takano K, Miyake T, Nishio T, Muto S, Koshizuka K, Nakagomi H, Kubo M, Tada Y.
    Journal: Pediatr Surg Int; 1998 Sep; 13(7):487-90. PubMed ID: 9716675.
    Abstract:
    Large abdominal wall defects may require a prosthesis for closure. The aim of our study was to identify the best material for abdominoplasty in pediatric patients. One hundred twenty-eight Wistar KY strain male rats (3 weeks old) were used. All animals underwent celiotomy via a midline skin incision. They were divided into seven groups as follows: the animals in groups 1 through 6 underwent full-thickness abdominal wall excision 3 cm in diameter. The animals in group 1 underwent primary closure. In groups 2 through 6 the defect was closed with prosthetic material. In Group 7, a sham operation was performed. Daily weights were measured. The animals were killed after 3 and 9 weeks. Adhesion scores were assigned for each group. Vicryl mesh resulted in the fewest adhesions and had no effect on weight gain in the developing rats.
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