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  • Title: Cytotoxic T cell responses to intracellular pathogens.
    Author: Stenger S, Modlin RL.
    Journal: Curr Opin Immunol; 1998 Aug; 10(4):471-7. PubMed ID: 9722925.
    Abstract:
    Host defense against intracellular pathogens is thought to require cytotoxic T cells. Recent studies have investigated the impact of host cell lysis and cytokine production by cytotoxic T lymphocytes on the fate of intracellular pathogens. The identification of two mechanisms of lysis induced by cytotoxic T lymphocytes--the granule exocytosis pathway and the Fas-FasL interaction--have provided new insight into the role of cytotoxic T lymphocyters in immunity to infection.
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