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  • Title: Use of pharmacologic immunosuppression to augment the specific unresponsiveness (tolerance) to skin allografts induced by donor-specific bone marrow in antilymphocyte serum-treated mice: the unique effect of sirolimus.
    Author: Hale D, Gottschalk R, Maki T, Monaco AP.
    Journal: Transplant Proc; 1998 Aug; 30(5):2432-4. PubMed ID: 9723527.
    Abstract:
    Tolerance produced with ALS treatment, DSBM, and sirolimus involves multiple mechanisms of a specific and nonspecific nature. In eventual clinical application for tolerance induction, sirolimus (rapamycin) has great potential for augmenting the tolerogenicity of the ALS/BM regimen.
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