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  • Title: The Bactrocera tryoni homologue of the Drosophila melanogaster sex-determination gene doublesex.
    Author: Shearman DC, Frommer M.
    Journal: Insect Mol Biol; 1998 Nov; 7(4):355-66. PubMed ID: 9723873.
    Abstract:
    A homologue of the bifunctional sex-determining gene, doublesex (dsx), has been identified in the tephritid fruit fly, Bactrocera tryoni, and has been found to be expressed in a sex-specific manner in adult flies. The male- and female-specific cDNAs are identical at their 5' ends but differ at their 3' ends and appear to be the products of alternate splicing. The level of identity of the sex-specific DSX proteins of B. tryoni with the D. melanogaster DSX proteins, across the region corresponding to the DNA binding domain and the oligomerization domains, is greater than 85%. Four sequence motifs which are ten to thirteen bases identical to the TRA/TRA-2 binding sites (thirteen-nucleotide repeat sequences) are present in the female-specific exon of the B. tryoni dsx gene.
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