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  • Title: [Semiologic, biochemical and electrophysiologic analysis of the stages of apopleptic coma].
    Author: Bogolepov NK, Fedin AI, Aristova RA, Dubrovskaia MK, Filippov MA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1976; 76(8):1127-37. PubMed ID: 973512.
    Abstract:
    The paper contains some results of a comprehensive clinical, biochemical and electrophysiological study of 120 patients with different stages of an apoplectic coma. The authors studied the gas content, acid-base balance of the cranial blood inflow and outflow in the CSF and changes of EEG and EMG. It was shown that there were different levels of CNS lesions (cortico-subcortical, meso-diencephalic, meso-pontile and bulbar level) which corresponded to certain correlations between clinical, biochemical, EEG and EMG findings. The authors describe a classificational scheme of 4 stages of an apopletic coma. Special significance in the pathogenesis of a coma along with structural lesions in the different areas of the CNS is attached to metabolic disturbances and extracerebral factors (respiratory and circulatory disorders).
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