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  • Title: [The evaluation of lymphocyte subpopulation by flow cytometry in healthy children].
    Author: Iwaszkiewicz-Pawłowska A, Stasiak-Barmuta A, Zak J.
    Journal: Wiad Lek; 1998; 51(5-6):238-43. PubMed ID: 9737188.
    Abstract:
    Seeing that amount of experiences concerning the cytometry of lymphocyte subpopulation in particular age ranges is very low we considered that undertaking this subject is useful. By the method of flow cytometry 49 children at the age from 2 months to 15 years were studied. According to the results of our studies we found, starting from the third year of life decrease of mean percentage values of cells CD19+, progressive in relation to the age, increase of mean percentage values of cells CD2+, increase of percentage values of cells CD8+ and cells CD56++ and the decrease of mean values of the indicator Th/Ts. Remaining CD3, CD4 did not show any statistically significant differences in investigated age ranges. Determined by the method of flow cytometry the percentage and complete values of lymphocyte subpopulations in peripheral blood in investigated age ranges can make the reference values in the assessment of immunological state.
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