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  • Title: [The correlation between serum thyroglobulin and iodine-131 scanning in detecting metastases in patients with a differentiated thyroid carcinoma].
    Author: Abduluakhab M, Gavrilov M, Mladenov B.
    Journal: Khirurgiia (Sofiia); 1997; 50(4):33-6. PubMed ID: 9739856.
    Abstract:
    One-hundred seventy-one patients, operated for differentiated thyroid gland carcinoma, are subjected to serum thyroglobulin assessment and whole-body scanning. In twenty-nine of the total of 171 patients there is evidence of relapses and metastases, discovered by either examination. In 27/29 cases with metastases (positive scan finding) a high serum thyroglobulin level is documented. The correlation between serum thyroglobulin level and whole-body scanning finding among patients without residual normal thyroid parenchyma (status post total thyroidectomy) is much more favourable than the one in patients presenting normal residual parenchyma (status post organ-salvaging operation). The conclusion is drawn that serum thyroglobulin contributes greatly to the diagnosis of recurrences and metastases, especially in patients with normal residual parenchyma missing.
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