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  • Title: [Chronic edema, monoclonal dysglobulinemia and profuse telangiectasia: a distinct entity?].
    Author: Castanet J, Lacour JP, Chartier C, Perrin C, Martin T, Grosshans E, Ortonne JP.
    Journal: Ann Dermatol Venereol; 1997; 124(10):717-20. PubMed ID: 9740872.
    Abstract:
    INTRODUCTION: Monoclonal gammopathy and edema are features encountered during several diseases, especially systemic capillary leak syndrome. The diagnoses of POEMS syndrome, edematous systemic scleroderma and a fortuitous association may be also discussed. We report the cases of two patients which did not fulfill the criteria for such diagnoses. CASE REPORT: Although the 2 cases share some discrepancies, they have also similar and particular features: association of chronic edema, monoclonal gammopathy and profuse and acquired telangiectasias. DISCUSSION: The meaning of these cases remains to be clarified. It might be an entity close to the systemic capillary leak syndrome but characterized by the chronicity of edema and by a distinct cutaneous sign, the occurrence of numerous telangiectasias. These cases emphasize that the acquired and profuse telangiectasias belong to the wide range of cutaneous abnormalities which may be associated with monoclonal paraproteinemia.
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