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  • Title: [Sulodexide in the treatment of diabetic nephropathy].
    Author: Rasovskiĭ BL, Tarasov AV, Trel'skaia NIu, Severina TI, Chernykh EF.
    Journal: Klin Med (Mosk); 1998; 76(7):40-2. PubMed ID: 9742778.
    Abstract:
    Sulodexide (Vessel 2F, Italy) was given to 20 patients with diabetes mellitus type I with initial nephropathy. Urine excretion of albumin significantly fell in 18 patients and remained so in 15 patients 6 weeks after the drug discontinuation. Plasma total cholesterol tended to lowering. No changes were registered in hemostasis and carbohydrate metabolism. The authors propose combined administration of sulodexide and inhibitors of angiotensin-converting enzyme for treatment and prevention of diabetic nephropathy progression.
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