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  • Title: Pseudo-Meigs' syndrome caused by paraovarian fibroma.
    Author: Giannacopoulos K, Giannacopoulou Ch, Matalliotakis I, Neonaki M, Papanicolaou N, Koumantakis E.
    Journal: Eur J Gynaecol Oncol; 1998; 19(4):389-90. PubMed ID: 9744733.
    Abstract:
    Meigs' syndrome includes an ovarian tumor, usually fibroma, associated with hydrothorax and ascites. It is accepted that uterine tumors, like fibromas, can also be associated with ascites and hydrothorax, but this is extremely rare. The mechanism of formation of peritoneal and pleural effusion is not well documented. The most likely pathogenesis ascribes the fluid formation to the filtration of interstitial fluid in the peritoneal through the tumor capsule, and the diffusion to the pleural space through the diaphragm lymphatic vessels at the foramen of Bochdalek. Paraovarian fibromas are also extremely rare neoplasms, probably of paramesonephric origin. It has been hypothesised that they can develop by proliferation of connective tissue cells around the Wolfian remnants. In this article, probably for the first time, a case of paraovarian fibroma with ascites and hydrothorax is presented.
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