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  • Title: Human parvovirus B19 infection resembling systemic lupus erythematosus.
    Author: Tanaka A, Sugawara A, Sawai K, Kuwahara T.
    Journal: Intern Med; 1998 Aug; 37(8):708-10. PubMed ID: 9745861.
    Abstract:
    A 39-year-old female visited our hospital because of morning stiffness, arthralgia, skin rash of the extremities and general fatigue. On examination, she also had a malar rash and an oral ulcer. Laboratory findings revealed that antinuclear antibodies were positive and complement component levels (C3, C4, CH50) were all low. Serology for human parvovirus B19 (HPV-B19) was positive for both immunoglobulin (Ig)M and IgG. Gradually, her symptoms improved and laboratory data returned to normal range without medications. This case suggests that HPV-B19 infection may be attributed to the pathogenesis of systemic lupus erythematosus.
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