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  • Title: [Infantile acne and isotretinoin].
    Author: Léauté-Labrèze C, Gautier C, Labbé L, Taieb A.
    Journal: Ann Dermatol Venereol; 1998 Feb; 125(2):132-4. PubMed ID: 9747233.
    Abstract:
    UNLABELLED: We report a case of severe infantile cystic acne, which required a treatment with oral isotretinoin. CASE REPORT: The patient, a 22-month-old boy, presented cystic acne since 6 months of age. The child was otherwise healthy and endocrine evaluation was normal. Previous treatments had no effect, oral isotretinoine led to cure without secondary effects. COMMENTS: The etiology of infantile acne is not clearly defined, but may result from a persisting androgen-driven stimulation of sebaceous glands. Oral isotretinoin is safe and effective in case of recalcitrant infantile acne, but close monitoring is necessary because of the well-known side effects of oral retinoids.
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