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  • Title: Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa.
    Author: Prinsep MR, Patterson GM, Larsen LK, Smith CD.
    Journal: J Nat Prod; 1998 Sep; 61(9):1133-6. PubMed ID: 9748382.
    Abstract:
    Two new porphinoids, tolyporphins J (1) and K (2), have been isolated from the terrestrial cyanobacterium, Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The activities of tolyporphins J and K in cell sensitization and drug accumulation assays for multidrug resistance (MDR) reversal were compared with those of tolyporphin A. Unusual NMR spectroscopic shifts were observed for tolyporphin J (1) in CDCl3.
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