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  • Title: [Primary hyperaldosteronism and adenoma of the adrenal cortex. Suppression of aldosterone with dexamethasone].
    Author: Bercovici JP, Roudaut N, Kerlan V, Aupetit-Faisant B, Floch HH.
    Journal: Ann Endocrinol (Paris); 1998 Apr; 59(1):20-2. PubMed ID: 9752394.
    Abstract:
    The aim of the study was to evaluate dexamethazone test in a patient with primary aldosteronism caused by an adrenocortical adenoma. We observed a 50% decrease of plasma aldosterone as in glucocorticoid suppressible aldosteronism (GSA) but absolute value of aldosterone remained higher than 40 pg/ml. Basal plasma and urinary values of 18 OXO and 18 OH cortisol were not significantly elevated as in GSA. Inversely, the evaluation of 11 beta-hydroxylase activity of mineralocorticoids was in favor of a benign adrenal tumor.
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