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  • Title: Early and long-term effects of chronic low-dose radiation and coenzyme Q diet on the proliferation of rat spleen T cells.
    Author: Novoselova EG, Semiletova NV, Makar VR, Gordon RYa.
    Journal: Indian J Biochem Biophys; 1998 Apr; 35(2):103-7. PubMed ID: 9753869.
    Abstract:
    Chronic whole-body irradiation (0.43 cGy/day; total doses 11, 23, and 35 cGy) caused non-monotonous long-term disturbances in rat splenic T lymphocytes proliferation. Immunosuppression observed after chronic exposure had no correlation with the splenic cell number and the decrease in the fluorescence intensity of Hoechst 33258-DNA complex in T lymphocytes. Small, but significant radioprotection was observed with Coenzyme Q diet immediately after irradiation. These results indicate that the changes in T cell immunity, T cell viability, and T cell DNA state after exposure to low dose radiation are not interrelated.
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