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  • Title: Severe hyponatremia, neuroleptic malignant syndrome, rhabdomyolysis and acute renal failure: a case report.
    Author: Elizalde-Sciavolino C, Racco A, Proscia-Lieto T, Kleiner M.
    Journal: Mt Sinai J Med; 1998 Sep; 65(4):284-8. PubMed ID: 9757749.
    Abstract:
    Acute renal failure secondary to myoglobinuria is a rare yet possible complication of malignant neuroleptic syndrome associated with the use of dopamine antagonists. We describe the case of a 42-year-old schizophrenic man who presented with severe hyponatremia, and proceeded to acute malignant neuroleptic syndrome, rhabdomyolysis, and acute renal failure. We contend that the acute hyponatremia may have served as a precipitating factor.
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