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  • Title: [Paraneoplastic intestinal pseudo-obstruction revealing small cell lung carcinoma: "the anti-Hu syndrome"].
    Author: Cuillerier E, Coffin B, Potet F, Dapoigny M, Flourie B, Coffin JC, Benyahia B, Bitoun A, Messing B, Rambaud JC.
    Journal: Gastroenterol Clin Biol; 1998 Mar; 22(3):346-8. PubMed ID: 9762221.
    Abstract:
    A 67-year-old woman was admitted for intestinal pseudoobstruction associated with peripheral sensitive neuropathy. Jejunal biopsies performed during laparotomy, showed axonal degeneration and lympho-plasmocytic infiltration in myenteric plexus. High titer of seric anti-Hu antibodies suggested a paraneoplastic syndrome. Thoracic CT scan showed mediastinal lymph nodes. Their histological examination confirmed the diagnosis of metastatic small-cell lung carcinoma. Her condition gradually deteriorated despite supportive parenteral nutrition, chemotherapy, steroids and intravenous immunoglobulins. She died 12 months after the onset of symptoms.
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