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  • Title: Scanning near-field optical microscopy in cell biology and microbiology.
    Author: Meixner AJ, Kneppe H.
    Journal: Cell Mol Biol (Noisy-le-grand); 1998 Jul; 44(5):673-88. PubMed ID: 9764739.
    Abstract:
    Scanning a point light source in close proximity over a sample and recording the scattered or transmitted light intensity point by point allows one to record optical images with a resolution not limited by diffraction. An overview of this technique called scanning near-field optical microscopy (SNOM or NSOM) is given with emphasis on cell- and microbiology. After an introduction, where the basic features of the technique are explained, illustrative examples are presented, such as a HeLa cell, fluorescence labelled human chromosomes, super resolution fluorescence imaging, single molecule imaging and fluorescence resonance energy transfer between a single pair of dye molecules.
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