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  • Title: Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113.
    Author: Höltzel A, Kempter C, Metzger JW, Jung G, Groth I, Fritz T, Fiedler HP.
    Journal: J Antibiot (Tokyo); 1998 Aug; 51(8):699-707. PubMed ID: 9766461.
    Abstract:
    A new secondary metabolite was detected in the culture filtrate and extracts of Streptomyces violaceusniger Tü 4113 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compound named spirofungin has a polyketide-spiroketal structure and shows various antifungal activities, particularly against yeasts.
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