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  • Title: Quantification of penicillin-G and procaine in equine urine and plasma using high-performance liquid chromatography.
    Author: Luo Y, McNamara B, Fennell MA, Teleis DC, May L, Rudy J, Watson AO, Uboh CE, Soma LR.
    Journal: J Chromatogr B Biomed Sci Appl; 1998 Sep 04; 714(2):269-76. PubMed ID: 9766866.
    Abstract:
    A rapid and sensitive method for the extraction and quantification of penicillin-G and procaine in horse urine and plasma samples has been successfully developed. The method involves the use of solid-phase extraction (SPE) for penicillin-G, liquid-liquid extraction (LLE) for procaine, and high-performance liquid chromatography (HPLC) for the quantification of penicillin-G and procaine. The new method described here has been successfully applied in the pharmacokinetic studies of procaine, penicillin-G and procaine-penicillin-G administrations in the horse.
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