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  • Title: Diphenylhydantoin inhibition of pentagastrin-stimulated calcitonin secretion in the pig.
    Author: Pento JT.
    Journal: Horm Metab Res; 1976 Sep; 8(5):399-401. PubMed ID: 976938.
    Abstract:
    The present study examined the influence of diphenylhydantoin (DPH) on pentagastrin-induced calcitonin (CT) secretion in the pig. Diphenylhydantoin was observed to slow the onset and prolong the duration of pentagastrin stimulation on CT secretion. Further, pentagastrin reduced plasma calcium in both the control and DPH treated groups. The results of this study indicate a significant DPH-induced inhibition of pentagastrin-stimulated CT secretion in the pig.
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