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  • Title: [Incidence and pattern of recurrent side effects in persons with different haptoglobin phenotypes during chemotherapy of pulmonary tuberculosis].
    Author: Ubaĭdullaev AM, Tashpulatova FK, Kazakov KS.
    Journal: Probl Tuberk; 1998; (4):23-4. PubMed ID: 9771032.
    Abstract:
    A total of 197 patients with pulmonary tuberculosis who had different haptoglobin phenotypes (Hp) were examined. Antituberculous agents were found to cause side effects in 145 patients during chemotherapy. In 82.7% of cases, adverse reactions occurred in patients with Hp 2-2 and Hp 1-1. Relapsing adverse reactions occurred mainly as allergic skin reaction and mixed syndrome. In 89% of cases, the pattern of relapsing adverse reactions did not coincide with the initial manifestations.
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