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  • Title: Interactions between malnutrition and primaquine studied on Wistar rats. II. Complex vitamin B deficiency and thiamine deficiency.
    Author: Oltersdorf U, Bitsch I, Klapp-Kunsemüller E.
    Journal: Int J Vitam Nutr Res; 1976; 46(3):356-65. PubMed ID: 977222.
    Abstract:
    The action of primaquine was investigated on male Wistar rats depleted on the vitamin B complex (approximately 50% of their requirement for optimal growth), on thiamine (approximately 50% of their requirement for optimal growth), and pair-fed control animals. There was only a marginal increase in adverse primaquine reactions in the malnourished, especially in the thiamine deficient rats.
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