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  • Title: Dilated uremic cardiomyopathy in a dialysis patient cured by persistent ultrafiltration.
    Author: Töz H, Ozerkan F, Unsal A, Soydas C, Dorhout Mees EJ.
    Journal: Am J Kidney Dis; 1998 Oct; 32(4):664-8. PubMed ID: 9774132.
    Abstract:
    A patient is presented who after 2 years of hemodialysis showed all of the features of congestive cardiomyopathy to a very severe degree: dilation of all cardiac compartments, increased left ventricular mass, low ejection fraction, diastolic disturbances, third- to fourth-degree mitral and tricuspid regurgitation, ascites, and low blood pressure. All of these abnormalities gradually but completely disappeared during 5 months of persistent ultrafiltration during or between dialysis sessions. It was concluded that chronic fluid overload was a major factor in the cardiac disease of this patient. Unrecognized hidden fluid overload has long been known (but also neglected), and its prevention deserves top priority in chronic dialysis patients.
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