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  • Title: Vascular control of nutrient delivery by flow redistribution within muscle: implications for exercise and post-exercise muscle metabolism.
    Author: Clark MG, Rattigan S, Newman JM, Eldershaw TP.
    Journal: Int J Sports Med; 1998 Aug; 19(6):391-400. PubMed ID: 9774206.
    Abstract:
    There is evidence for non-nutritive flow routes within, or associated with, skeletal muscle. Large capillary-like structures are possible candidates. The proportion of flow distributed between nutritive and non-nutritive routes appears to be tightly regulated and can control muscle metabolism and contraction by regulating delivery and product removal. The portion of flow that is carried by the non-nutritive routes at rest affords a flow reserve for amplifying nutrient delivery as muscle begins to work and may determine post-exercise metabolism. Inappropriate signals, however, may diminish nutritive flow to the detriment of muscle performance and post-exercise recovery. New technologies should allow the identification of the non-nutritive routes.
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