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  • Title: Benzodiazepine binding site-interactive flavones from Scutellaria baicalensis root.
    Author: Liao JF, Wang HH, Chen MC, Chen CC, Chen CF.
    Journal: Planta Med; 1998 Aug; 64(6):571-2. PubMed ID: 9776664.
    Abstract:
    A benzodiazepine binding assay directed separation led to the identification of 3 flavones baicalein (1), oroxylin A (2), and skullcapflavone II (3) from the water extract of Scutellaria baicalensis root. Compounds 1, 2, and 3 interacted with the benzodiazepine binding site of GABAA receptors with a Ki value of 13.1, 14.6 and 0.36 micromol/L, respectively.
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