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  • Title: [The P300 component of the auditory evoked potential in the posttraumatic vegetative state].
    Author: Sharova EV, Oknina LB, Potapov AA, Zaĭtsev OS, Masherov EL, Kulikov MA.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1998; 48(4):719-30. PubMed ID: 9778815.
    Abstract:
    The dynamic studies of P300 component of the acoustic evoked potential were conducted in 12 patients in posttraumatic state of the autonomic system. The amplitude and time parameters of P300 were analyzed, its spatial distribution over the cortex, and features of generation. The obtained results were compared with the normative data. Significant changes in P300 in comparison with the normal characteristics were revealed in patients with the absence of conscious mental activity. These changes were maximally expressed when the state of patients was irreversible. In case of patients' outcome from the studied state the amplitude-temporal and topographic response characteristics tended to normalization but did not reach it completely. The obtained results allow us to consider the P300 component as one of the most informative indices in consciousness recovery after severe brain injury.
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