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  • Title: [Diagnostic efficacy of myocardial tomographic imaging in the detection of restenosis after coronary angioplasty].
    Author: Candell-Riera J, de la Hera JM, Santana-Boado C, Castell-Conesa J, Aguadé-Bruix S, Bermejo B, Angel J, Anívarro I, Soler-Soler J.
    Journal: Rev Esp Cardiol; 1998 Aug; 51(8):648-54. PubMed ID: 9780779.
    Abstract:
    INTRODUCTION AND OBJECTIVES: To analyze the efficacy of single photon emission tomography (SPET) with 99mTc-compounds for the diagnosis of restenosis of previous percutaneous transluminal coronary angioplasty (PTCA). PATIENTS AND METHODS: Seventy-one patients (16 women, median age: 60 years, 35 with multivessel disease, 78 arteries with PTCA) with previous PTCA and with coronary angiography performed after scintigraphy were studied. 99mTc-SPET exercise (53 with MIBI and 18 with tetrofosmin) was performed, for clinical reasons, to all patients between one month and 4 years after PTCA. Intravenous dipyridamole was administered simultaneously to 16 patients who had insufficient exercise. RESULTS: SPET sensitivity, specificity, positive predictive values, negative predictive values and global values were all significantly higher than those obtained with exercise tests (80% vs 63%; p = 0.05; 83% vs 37%; p = 0.001; 91% vs 69%; p = 0.007; 64% vs 31%; p = 0.009, and 81% vs 55%; p = 0.0006, respectively). These results were significantly superior in patients with one vessel disease than in patients with multivessel disease. CONCLUSIONS: SPET exercise with 99mTc-compounds is a test with a high efficacy for the diagnosis of post-PTCA restenosis, mainly in patients with one vessel disease.
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