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  • Title: Myofibrillar protein pattern in experimental myotonia in rats.
    Author: Niebrój-Dobosz I, Kwieciński H, Kamińska A.
    Journal: J Neurol Sci; 1976 Oct; 29(2-4):241-7. PubMed ID: 978209.
    Abstract:
    Experimental myotonia was induced in rats by long-term administration of 20,25-diazacholesterol. Electrophysiological, morphological and biochemical investigations were carried out on m. soleus, m. extensor digitorum longus and m. gastrocnemius. The effect of 20,25-diazacholesterol administration on myofibrillar proteins was studied and a significant rise in the concentration of a protein presumed to be alpha-actinin was demonstrated in m. gastrocnemius. A change of the same character, not statistically significant, was observed in the m. extensor digitorum longus.
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