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  • Title: Bullous erythema multiforme following herpes zoster and varicella-zoster virus infection.
    Author: Weisman K, Petersen CS, Blichmann CW, Nielsen NH, Hultberg BM.
    Journal: J Eur Acad Dermatol Venereol; 1998 Sep; 11(2):147-50. PubMed ID: 9784041.
    Abstract:
    Four cases of herpes zoster-induced bullous erythema multiforme (EM) are reported. Three patients presented with widespread skin lesions 10 to 14 days after an episode of thoracic herpes zoster. In these patients a high increase in varicella-zoster virus (VZV) antibody titer was detected, indicating secondary VZV infection. Histologic examinations of skin biopsy from a patient with widespread lesions (case 4) revealed a mixture of EM, toxic epidermal necrolysis and herpetic virus infection. VZV should be included in the list of infectious agents able to trigger EM and Stevens-Johnson syndrome.
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