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  • Title: Efficacy of cyclosporine plus etretinate in the treatment of erythrodermic psoriasis (three case reports).
    Author: Kokelj F, Plozzer C, Torsello P, Trevisan G.
    Journal: J Eur Acad Dermatol Venereol; 1998 Sep; 11(2):177-9. PubMed ID: 9784049.
    Abstract:
    BACKGROUND: Association of different treatments are often used in erythrodermic psoriasis in order to increase the effectiveness and decrease the incidence of side effects due to single drugs. MATERIALS AND METHODS: Three in-patients affected by erythrodermic psoriasis, not responding to cyclosporine, (two patients) and etretinate, (one patient), were treated with the association cyclosporine plus etretinate. RESULTS: Clinical response was prompt to the combined therapy. The two drugs were tapering off gradually over 6 months; the patients maintained the remission for prolonged period. CONCLUSIONS: Combined cyclosporine-etretinate therapy may be considered as an effective and well tolerated treatment of erythrodermic psoriasis in patients not responding to monotherapy regimen.
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