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  • Title: Radiologic and scintiscan findings in HLA-B27 negative patients with ankylosing spondylitis.
    Author: Russell AS, Lentle BC, Schlaut J.
    Journal: J Rheumatol; 1976 Sep; 3(3):321-3. PubMed ID: 978668.
    Abstract:
    Of 189 consecutive patients seen with definite ankylosing spondylitis, 17 did not possess the transplantation antigen HLA-B27. These 17 patients had less severe radiological evidence of disease than the group as a whole, or a sub-group matched for age, sex, and duration of disease. This supports the suggestion that the HLS-B27 antigen itself may play a role in the pathogenesis of the disease, and does not serve merely as a marker for a linked immune response gene.
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