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  • Title: Thyroid volume is progressively reduced as a sequela of neck irradiation for childhood Hodgkin's disease.
    Author: Bossi G, Larizza D, Sommaruga G, Corbella F, Klersy C, Aricò M.
    Journal: Haematologica; 1998 Aug; 83(8):754-6. PubMed ID: 9793265.
    Abstract:
    Thyroid volume reduction was observed, among 25 subjects off-therapy after Hodgkin's disease. The volume reduction was related to dose (p = 0.014) and time from radiotherapy (p = 0.01). The correlation was very specific since all patients with reduced volume had hypothyroidism, but not very sensitive since 25% of subjects with thyroid dysfunction had normal gland volume.
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