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Title: Postantibiotic effect and postantibiotic sub-MIC effect of quinupristin-dalfopristin against gram-positive and -negative organisms. Author: Pankuch GA, Jacobs MR, Appelbaum PC. Journal: Antimicrob Agents Chemother; 1998 Nov; 42(11):3028-31. PubMed ID: 9797249. Abstract: Quinupristin-dalfopristin produced postantibiotic effects (PAEs) and postantibiotic sub-MIC effects of >2 h against 18 gram-positive cocci. Mean pneumococcal and staphylococcal PAEs were 2.8 and 4.7 h, respectively, with shorter PAEs for constitutively than inducibly macrolide-resistant staphylococci. Mean PAEs for vancomycin-susceptible and -resistant Enterococcus faecium were 8.5 and 2.6 h, respectively.[Abstract] [Full Text] [Related] [New Search]