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  • Title: Single-layer closure for typhoid perforations of the small intestine: case report.
    Author: Connolly DP, Ugwu BT, Eke BA.
    Journal: East Afr Med J; 1998 Jul; 75(7):439-40. PubMed ID: 9803640.
    Abstract:
    The case of a 13-year old girl who presented with generalised peritonitis, septic shock and laboratory features of perforated typhoid enteritis is presented. At laparotomy 25 perforations involving the distal jejunum and the entire ileum were noted with extensive peritoneal soilage. The perforations were successfully closed in single layer using vicryl (polyglactin 910) sutures and the peritoneum thoroughly lavaged. The patient has been followed up for thirty months with only minimal complications. We believe that single layer closure of extensive multiple typhoid perforations in a poor risk patient when weighed against resection and anastomosis with the possibility of short bowel syndrome is safer, quicker and more effective as long as the procedure is undertaken after adequate resuscitation and under appropriate antibiotic cover.
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