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  • Title: [Secondary mitochondrial diseases].
    Author: Cardellach F, Casademont J, Urbano-Márquez A.
    Journal: Rev Neurol; 1998 Apr; 26 Suppl 1():S81-6. PubMed ID: 9810594.
    Abstract:
    OBJECTIVE: To analyze the secondary mitochondriopathies, which are processes characterized by the presence of structural and/or functional abnormalities of mitochondria whose causes may be assumed to be situated outside these organella. DEVELOPMENT: These processes will be categorized in the following groups; 1. Specific deficiency of a intermediate metabolite or cofactor; 2. Endocrinopathies; 3. Ischemia-reperfusion; 4. Sepsis; 5. Toxins; 6. Drugs; 7. Mitochondrial respiratory chain deficiency; 8. Ageing, and 9. Oncogenesis and apoptosis. CONCLUSION: The better understanding of secondary mitochondriopathies may allow to eliminate the cause of them and sometimes to establish the appropriate treatment.
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