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  • Title: Analysis of the length distribution of murein glycan strands in ftsZ and ftsI mutants of E. coli.
    Author: Ishidate K, Ursinus A, Höltje JV, Rothfield L.
    Journal: FEMS Microbiol Lett; 1998 Nov 01; 168(1):71-5. PubMed ID: 9812365.
    Abstract:
    The chain length distribution of murein glycan strands was analyzed in wild-type cells and in cells in which preseptal and/or septal murein synthesis was prevented in ftsZ84 and ftsI36 mutants of E. coli. This revealed a significant change in glycan chain lengths in newly synthesized murein associated with inactivation of the ftsZ gene product but not with inactivation of the ftsI gene product. This is the first reported abnormality in murein biosynthesis associated with mutation of an essential cell division gene.
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