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  • Title: [Increase in the level of augmenter of liver regeneration mRNA in the rat regenerating liver after partial hepatectomy].
    Author: Yang XM, Xie L, Wu ZZ, Wu CT, He FC.
    Journal: Sheng Li Xue Bao; 1997 Oct; 49(5):599-601. PubMed ID: 9813504.
    Abstract:
    Augmenter of liver regeneration (ALR) is a novel hepatic stimulator. After 70% of the rat liver was removed, ALR-like activity in the remnant liver began to increase within 24 h. In parallel with the activity, the ALR mRNA level in the remnant liver increased 12 h after the operation and reached a maximum in 24 h. These findings indicate that the liver itself produces ALR, which may be a hepatotropic factor acting as a trigger for liver regeneration.
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