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  • Title: Cytotoxic T cell responses to a syngeneic tumour: conditions for primary activation in vitro.
    Author: Warren HS, Woolnough JA, Lafferty KJ.
    Journal: Aust J Exp Biol Med Sci; 1978 Apr; 56(2):247-51. PubMed ID: 98140.
    Abstract:
    Primary cytotoxic responses of DBA/2 lymph node cells to a syngeneic tumour (the mastocytoma P815) have been generated in vitro. The development of these responses is dependent on the addition of a soluble factor (CSCS) which is produced by concanavalin A-activated spleen cells. The response is mediated by T lymphocytes, can be detected at low effector to target cell ratios and is directed against P815 tumour-associated antigens.
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