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  • Title: Action of methoxyflurane on intraocular pressure (IOP) and acid-basic equilibrium in the dog.
    Author: Vassilieff I.
    Journal: Rev Bras Pesqui Med Biol; 1976 Sep; 9(4):207-12. PubMed ID: 981740.
    Abstract:
    MEthoxyflurane pulmonary inhalation administered to dogs, 2 ml/10kg/5 min, after 10 minutes caused a significant increase (13.3 mmHg) in intraocular pressure as well (6 mmHg) in venous pressure and a significant fall, of 23.3 mmHg, in arterial pressure and in respiratory frequency, of 3.2 per min and amplitude of 7.1 mm. On the other side, as acid-basic equilibrium alterations in blood, were observed a fall of 0.13 of pH and an increase of 18.3 mmHg of pCO2 and of 2.7 mEq/l of bicarbonate concentration.
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