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  • Title: Antitumor activity of paclitaxel and epirubicin in human breast carcinoma, R-27.
    Author: Asanuma F, Yamada Y, Kawamura E, Lee K, Kobayashi H, Yamada T, Suzuki T, Kubota T.
    Journal: Folia Microbiol (Praha); 1998; 43(5):473-4. PubMed ID: 9821299.
    Abstract:
    The antitumor effect of paclitaxel, epirubicin, and both in combination was tested using R-27, an estrogen receptor-positive human breast carcinoma. In an in vivo study using nude mice both drugs showed an additive effect, whereas they showed a supraadditive pattern in in vitro MTT assay. The combination of paclitaxel and epirubicin may enhance the antitumor effect on breast carcinoma.
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