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Title: Side-effects of high pressure irrigation. Author: Wheeler CB, Rodeheaver GT, Thacker JG, Edgerton MT, Edilich RF. Journal: Surg Gynecol Obstet; 1976 Nov; 143(5):775-8. PubMed ID: 982257. Abstract: This study was undertaken to identify side-effects of high pressure irrigation. Standardized surgical wounds made in Yorkshire pigs were subjected to high pressure syringe and pulsatile irrigation. As a result of these treatments, fluids were disseminated into the adjacent tissue of the wound, predominantly in a lateral direction. Bacteria did not accompany this disseminated fluid and apparently were filtered out by the surface tissues. This treatment results in a tissue injury which impairs its defenses, making the wound more susceptible to infection. However, the remarkable cleansing capacity of high pressure irrigation appears to outweigh this side-effect, since heavily contaminated wounds subjected to this treatment heal per primum without infection.[Abstract] [Full Text] [Related] [New Search]