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  • Title: [Toxic epidermal necrolysis after treatment with lamotrigine].
    Author: Zachariae CO, Fogh K.
    Journal: Ugeskr Laeger; 1998 Nov 09; 160(46):6656-7. PubMed ID: 9825684.
    Abstract:
    A case of toxic epidermal necrolysis following treatment with lamotrigine is presented. A 20 year old male suffering from epilepsy was treated with lamotrigine in addition to valproic acid. After three weeks he developed cutaneous manifestations of Steven-Johnson's syndrome followed by toxic epidermal necrolysis, mucosal lesions and liver symptoms. He was treated with systemic corticosteroids, antibiotics and intravenous fluid, and recovered after a few weeks.
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