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  • Title: Increased resistance of an interferon-resistant cell subline to the toxic effect of double-stranded RNA.
    Author: Lackovic V, Borecký L.
    Journal: Acta Virol; 1976 Aug; 20(4):347-8. PubMed ID: 9826.
    Abstract:
    The toxicity of double-stranded (ds) f2-phage RNA for interferon-treated L cells and an interferon-resistant subline of L cells (CVS cells) was compared. The interferon-resistant subline proved to be about 20 times more resistant to ds RNA than the parent L cells. The degree of toxicity of ds RNA was dependent on the concentration of interferon to which the cells were exposed.
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