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  • Title: [Structure and function of hepatocyte lysosomes and peroxisomes of rachitic rats].
    Author: Khomutovskiĭ OA, Mironova VN, Degtiareva II.
    Journal: Ukr Biokhim Zh; 1976; 48(4):437-40. PubMed ID: 982611.
    Abstract:
    The submicroscopic organization and activity of acid phosphatase and catalase in lysosomes and peroxisomes of the rat hepatocytes were studied with experimental rachitis. It is determined that total and free activity of acid phosphatase in the liver tissue and certain lysosomes with rachitis increases whereas the catalase activity in the tissue and certain peroxisomes decreases. Permeability of the lysosome and peroxisome membranes rises for enzymes and cations. The process of peroxisome differentiation with rachitis is disturbed: there appear peroxisomes containing the marginal plates, that is not peculiar to the redont peroxisomes.
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