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  • Title: Isolation of translactone-containing triterpenes with thrombin inhibitory activities from the leaves of Lantana camara.
    Author: O'Neill MJ, Lewis JA, Noble HM, Holland S, Mansat C, Farthing JE, Foster G, Noble D, Lane SJ, Sidebottom PJ, Lynn SM, Hayes MV, Dix CJ.
    Journal: J Nat Prod; 1998 Nov; 61(11):1328-31. PubMed ID: 9834145.
    Abstract:
    Methanolic extracts prepared from the leaves of Lantana camara have been found to inhibit human thrombin. An assay, in which thrombin activity is measured as a function of clot formation from fibrinogen, was used to guide the fractionation and purification of five principal active constituents (1-5), which were all characterized as 5,5-trans-fused cyclic lactone-containing euphane triterpenes.
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