These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts.
    Author: Disch A, Rohmer M.
    Journal: FEMS Microbiol Lett; 1998 Nov 15; 168(2):201-8. PubMed ID: 9835029.
    Abstract:
    The biosynthesis of isopentenyl diphosphate, the central intermediate of isoprenoid formation, was investigated in the fungus Aschersonia aleyrodis and the yeast Rhodotorula glutinis. The incorporation of 13C-labeled glucose or acetate into their isoprenoids showed that ergosterol in both micro-organisms, ubiquinone in R. glutinis and dihydro-ubiquinone, beta-carotene and triterpenes of the hopane series in A. aleyrodis were synthesized via the mevalonate pathway. No evidence for the presence of the alternative mevalonate-independent glyceraldehyde 3-phosphate/pyruvate pathway was found.
    [Abstract] [Full Text] [Related] [New Search]